![]() A sialidase mutant displaying trans-sialidase activity. ↑ Paris G, Ratier L, Amaya MF, Nguyen T, Alzari PM, Frasch AC.Trans-sialidase: a unique enzyme activity discovered in the protozoan Trypanosoma cruzi. Specific alteration of NCAM-mediated cell adhesion by an endoneuraminidase. ↑ Rutishauser U, Watanabe M, Silver J, Troy FA, Vimr ER.Neuraminidase is important for the initiation of influenza virus infection in human airway epithelium. ↑ Matrosovich MN, Matrosovich TY, Gray T, Roberts NA, Klenk HD.The biological assembly of H5N1 avian influenza virus neuraminidase is. In Chagas disease trans-sialidase on the surface of Trypanosoma cruzi participate in host-parasite interactions and mediate the initial stages of the invasion of the host cell. The viral NAN is a drug target for prevention of influenza. Treatments:Neuraminidase Inhibitor Pharmacokinetics References.Carbohydrate binding domain from Streptococcus pneumoniae NanA sialidase complexed with 3'-sialyllactose.Neuraminidase Inhibitor Pharmacokinetics. ![]() User:Michael Strong/H1N1/NA/MSA for multiple sequence alignment.User:Michael Strong/H1N1/NA for Influenza virus neuraminidase.Lattice-translocation defects in some specific crystals of the catalytic head domain of influenza neuraminidase.Avian Influenza Neuraminidase, Tamiflu and Relenza.Anhydrosialidase catalyzes the elimination of sialyl group in N-acetylneuraminic acid glycosides to yield 2,7-anhydro-α-N-acetylneuraminate.This enzyme is a modified sialidase which has transglycosidase activity and transfers sialic acid from host glycoconjugates to β-galactose on a parasite surface. Trans-sialidase transfers sialic acid from Trypanosoma cruzi to a host cell.Pseudaminidase is a Pseudomonas aeruginosa neuraminidase.endo-neuraminidase is a phage neuraminidase which cleaves α-2,8-polysialic acid.The non-viral neuraminidase is called Sialidase. Neuraminidase or sialidase (NAN) is a viral neuraminidase which cleaves the glycosidic bonds of neuraminic acid.
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